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Mother-to-Child Transmission (MTCT) is a major route of Hepatitis B Virus (HBV) transmission, accounting for a substantial proportion of new infections, particularly in highly endemic areas. The timely adminis...
Congenital diaphragmatic hernia (CDH) and bronchopulmonary sequestration (BPS) are rare congenital anomalies that can coexist, with studies suggesting that 25–40% of CDH cases are accompanied by BPS. The assoc...
Patients with thalassemia acquire cellular oxidative damage mainly from the degradation of excessive uncoupled hemoglobin (Hb) chains and iron overload. The oxidative damage of red blood cells (RBCs) and plate...
Biliary obstruction is a rare complication in patients with hereditary spherocytosis (HS). The clinical course and optimal treatment strategies for HS patients complicated by biliary obstruction remain unclear.
Worldwide, neonatal mortality is a major public health burden especially in the developing countries. Several factors are associated with neonatal mortality at the neonatal intensive care unit (NICU). The aim ...
Fathers’ involvement in the care of preterm babies has been associated with good health outcomes for the mother and the baby. However, fathers’ involvement in the Neonatal Unit (NU) in Uganda remains sub-optim...
This scoping review aimed to identify methodological procedures for acquiring and analyzing ultrasound images of the tongue during sucking in full-term infants. The Participants, Concept, and Context strategy ...
Infection by the SARS-CoV-2 virus can cause coronavirus disease 2019 (COVID-19) and can also exacerbate the symptoms of Kawasaki disease (KD), an acute vasculitis that mostly affects children. This study used ...
To improve the nutritional management of premature infants in neonatal intensive care units (NICUs), we developed and implemented a standardized parenteral nutrition (PN) protocol aimed at optimizing early mac...
Only isolated occurrences of neonatal Jka hemolytic disease have been identified, and no cases of Jka hemolytic disease combining fetal and neonatal alloimmune thrombocytopenia (FNAIT) have been reported. The maj...
This investigation was designed to assess the mediating effects of physical exercise and depression on the relationship between family support and Internet addiction (IA) among adolescents in Western China.
As a heterogeneous syndrome, acute respiratory distress syndrome (ARDS) patients with comorbidities are significantly more severely ill. We aim to investigate the clinical characteristics and analyze the risk ...
Safe radiological practices are essential in pediatric healthcare because of children’s vulnerability to the chronic impacts of radiation exposure. Having sufficient knowledge is crucial for adopting radiologi...
Although paediatric depression is a recognised problem worldwide, there is limited data on its prevalence in children aged under 5 years, and the role of breastfeeding and medicinal exposure. This study examin...
Undernourished children are at risk of mortality and infection and tend to present with impaired cognitive and physical development with potentially lower physical fitness and motor skill competence. This meta...
Kawasaki disease (KD) is an acute immune-mediated vasculitis primarily affecting coronary arteries, with limited specific diagnostic biomarkers available. Chitinase protein-40 (YKL-40), a glycoprotein secreted...
This study evaluated the diagnostic value of complement levels in neonatal sepsis and their roles in disease progression.
Obesity is associated with chronic liver disease, which is why improved non-invasive diagnostic assessment of liver affection is desirable. The ultrasound-based biomarkers Attenuation Imaging coefficient (ATI)...
Shone’s complex (SC) comprises multi-level left-sided obstructive cardiac lesions. Limited research has addressed SC in the pediatric age, especially the factors impacting outcomes. Therefore, the current work...
Gastric lipomas are rare benign gastric tumors, with pediatric and adolescent cases being exceptionally uncommon. This report describes a case of a 17-year-old girl with a giant gastric lipoma (> 8 cm) and the...
Anemia of prematurity is a common concern for extremely low birth weight (ELBW) patients in the neonatal intensive care unit. The hemoglobin threshold at which the benefits of red blood cell transfusion outwei...
Asthma is the most common chronic illness in children and is characterized by airway hyperresponsiveness, increased production of mucus, and significant inflammation. The signal transducer and activator of tra...
Anemia of prematurity (AOP) is a common issue in neonatal intensive care units (NICUs) globally, associated with significant morbidity and mortality. Near-infrared spectroscopy (NIRS) has emerged as a noninvas...
Preoperative anxiety is a significant concern for pediatric patients undergoing surgery, often leading to adverse physiological, emotional, and postoperative outcomes. Traditional pharmacological approaches, w...
Preterm birth is a leading cause of childhood mortality and developmental disabilities, with persistent socioeconomic disparities in incidence and outcomes. Maternal presence during prolonged neonatal intensiv...
Right ventricle (RV) dysfunction because of pulmonary vasculopathy is the most common cause of death in sickle cell disease (SCD). This study aimed to explore the diagnostic accuracy of blood-speckle tracking ...
The correlation between parental and child physical activity levels has been the subject of significant investigation. Existing research has illuminated this association, particularly emphasising its influence...
Kawasaki disease (KD) is an acute systemic vasculitis primarily affecting children under five years old. While its etiology remains unclear, immune dysregulation has been implicated, suggesting a potential lin...
Fatigue is increasingly recognised as a prevalent and debilitating symptom for children and young people (CYP) with long-term conditions (LTCs), significantly affecting their family, social and educational par...
The increasing myopia of children has sparked speculations on whether the use of smartphones can accelerate this rate. This study aims to identify possible predictors for myopic progression in children with sm...
As the increasing survival of preterm infants bearing lower gestational age (GA) and birth weight (BW), new challenges have emerged regarding their management and prognosis. In low- and middle-income countries...
Preeclampsia is linked to fetal growth restriction and may have long-term implications for the offspring. Despite its significance, the fundamental mechanisms remain inadequately elucidated. The objective of t...
This study aimed to describe epidemiological changes of common respiratory pathogens in children with acute respiratory infections (ARIs) during the different levels of non-pharmaceutical interventions(NPIs).
Blau syndrome (BS) is a rare autoinflammatory disease characterized by a clinical triad of uveitis, dermatitis and arthritis. The aim of our study was to summarize organ involvement, predict disease prognosis ...
Coarctation of the aorta (CoA) is one of the more prevalent congenital heart diseases (CHD). The conventional treatment approach involves surgical correction of the coarctation. This procedure, however, can be...
Parents of children with a health condition experience high levels of distress which can have long-term impact on the child and parent. Dyadic interventions have the potential to decrease this distress, howeve...
This study explores ocular manifestations in children with mutations in key tumor suppressor genes (RB1, NF1, NF2, VHL, TSC1/2), which are linked to common pediatric hereditary cancer syndromes. Mutations in t...
Lower urinary tract symptoms (LUTS) are common in pediatric patients and significantly affect children’s well-being and family-related quality of life. However, no validated Chinese assessment tool for LUTS ex...
Hearing impairment (HI) is a prevalent problem. The majority of cases have HI during the neonatal period, while the still cases have incidence up to adolescents. Hearing amplification is a promising modality t...
Claes-Jensen syndrome (CJS) is a rare X-linked intellectual disability caused by mutations in the KDM5C gene, encoding a histone demethylase involved in chromatin remodeling and neurodevelopment. Males with he...
Despite global efforts to promote breastfeeding, the rate of exclusive breastfeeding (EBF) has remained stagnant in recent decades. Identifying factors that influence EBF is crucial. Therefore, this study aime...
To evaluate the impact of the Kangaroo Mother Care method on weight gain in premature newborns.
The global rise in pediatric hypertension (HTN) is a significant concern as it serves as a precursor to cardiovascular disease (CVD). To address this, we performed a comparative analysis of two guidelines for ...
Perforated peptic ulcers (PPU) represent a significant complication of peptic ulcers, associated with high mortality. As no systematic review of the literature on PPU in children currently exists, this study a...
To investigate the clinical and genetic characteristics of classic congenital adrenal hyperplasia (CAH) patients. To determine whether gonadotropin-releasing hormone analogs (GnRHa) + recombinant human growth ...
Predicting fluid responsiveness is challenging in infants. It is however crucial to avoid unnecessary volume expansion, which can lead to fluid overload. We tested the hypothesis that the stroke volume changes...
To investigate the efficacy of external fixation in treating unstable pelvic fractures in children and identify risk factors for poor prognosis.
Asthma is a heterogeneous disease. Precise and personalized treatment is urgently needed to reduce the disease’s burden. Thus, exploring the different types of airway inflammation in hospitalized children with...
This study aimed to investigate the genetic etiology and clinical features of non-syndromic pediatric obesity in a large Chinese cohort, providing insights into the genetic profile and its correlation with cli...
Polymelia, or accessory limb, is a rare congenital abnormality with unknown etiology. Here we report the case of an infant with an accessory limb, review the diagnostic and therapeutic consideration of such ca...
Citation Impact 2023
Journal Impact Factor: 2.0
5-year Journal Impact Factor: 2.4
Source Normalized Impact per Paper (SNIP): 0.972
SCImago Journal Rank (SJR): 0.688
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